Symbol
Name
ID

Sik3
SIK family kinase 3
MGI:2446296

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Mouse Phenotypes

increased eosinophil cell number

decreased erythrocyte cell number

decreased hematocrit

increased mean corpuscular hemoglobin

increased red blood cell distribution width

increased granulocyte number

thrombocytopenia

increased mean platelet volume

increased plasmacytoid dendritic cell number

decreased early germinal center B cell number

decreased germinal center B cell number

increased follicular B cell number

decreased KLRG1-positive NK cell number

decreased Ly6C-positive mature NK cell number

increased memory-marker NK cell number

decreased NK cell number

increased NK cell number

increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number

increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number

decreased CD4-positive, alpha-beta T cell number

increased CD8-positive, naive alpha-beta T cell number

increased KLRG1+ CD8 alpha-beta T cell number

increased CD8-positive, alpha-beta T cell number

increased KLRG1-positive CD4-negative NK T cell number

decreased memory-marker CD4-negative NK T cell number

increased CD4-negative NK T cell number

decreased memory-marker CD4-positive NK T cell number

decreased CD4-positive NK T cell number

increased Ly6C-positive NK T cell number

decreased NK T cell number

decreased alpha-beta T cell number

decreased KLRG1-positive T-helper cell number

increased KLRG1-positive T-helper cell number

decreased effector memory T-helper cell number

increased effector memory T-helper cell number

decreased T-helper cell number

decreased CD5-positive gamma-delta T cell number

increased memory-marker gamma-delta T cell number

decreased gamma-delta T cell number

decreased regulatory T cell number

decreased T cell number

Availability

Mouse Genotype

Sik3^{tm1a(EUCOMM)Hmgu}/Sik3^{tm1a(EUCOMM)Hmgu}

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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